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Colchicine poisoning resulting
from accidental ingestion of meadow saffron (Colchicum
autumnale).
Sannohe S, Makino Y, Kita T, Kuroda N,
Shinozuka T.
Department of Forensic Medicine, Hirosaki
University School of Medicine, Aomori, Japan.
A rare case of
colchicine poisoning resulting from accidental ingestion of meadow
saffron (Colchicun Autumnale) is reported. The plant can frequently be
found in the woods of the Northern Hemisphere (1), also in Japan. A
48-year-old male was admitted to hospital complaining of vomiting,
nausea and diarrhea following ingestion of the plant and died in four
days. The most striking histological findings were metaphasic mitotic
figures in the mucosa of the large intestine and the liver. Colchicine
was detected in the bile with high-performance liquid
chromatography/sonicspray ionization mass spectrometry
(HPLC/SSI-MS).
Publication Types:
PMID: 12455670 [PubMed - indexed for
MEDLINE]
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